I've been on (a fairly high dose of) lithium since 1997, and done well with it. Thyroid issues - yes; thirst - yes - but thyroid issues run in my family anyway, and II drinks tons of ice water every day.

Way back then my doctor said "lithium will make you feel better, but you will fight weight all your life."

Fat or crazy - easy choice for me! (And you don't really have to choose between the two.)