Going off meds while unstable? Do you think your meds are causing your depression? I tried to go med free. It did not work out. As I was taking myself slowly off the meds, my depression went right through the floor. The doctor gave me two choices. Either be med free or be stable. My vote went to being stable. But then I cannot take risks. I have too much daily responsibility which I can never ignore. Not even for one day. So I cannot have any down time. But this may not be the situation with you.