oh - meant to include this:
SNRI List: Serotonin Norepinephrine Reuptake Inhibitors
Below are different ratios of serotonin to norepinephrine reuptake inhibition. As you can see, Effexor has the most lop-sided ratio. Newer drugs like Cymbalta and Pristiq slightly bridged the gap, but still focus more on serotonin than norepinephrine. The latest SNRI approved for depression called Fetzima favors the norepinephrine, but has almost an equally balanced ratio.
- Effexor – (30:1)
- Cymbalta – (10:1)
- Pristiq – (10:1)
- Fetzima – (1:2)