Negative evidence here, but no, I don't have any problems with the flu shot. My arm barely gets sore and I don't notice any symptoms from it.

I have fibromyalgia, chronic fatigue syndrome, psoriatic arthritis, and depression.

I get a flu shot every year. Even though I don't seem to catch things terribly easily, if I do get something, it lasts about 3 times as long as average.

I don't know what causes people to react to the flu shot. I know very healthy people who get it and it makes them so sick the end up missing part of a day of work. It's a mystery to me.

I might not get one if I were you. If you do get flu, if you get Tamiflu right away, it's not nearly so bad.