I went from 104 lbs to 140 on Seroquel within 2 months. I begged the Dr. to change my med to something else. He refused. I told him I was always a tiny person and that I was basically living on breadcrumbs to control the weight gain.. You know what he said to me? EAT LESS BREAD CRUMBS!! How insensitive. Whats the point of an antidepressant if you hate your image everytime you look into a mirror?? It's just adding insult to injury. I dropped him ASAP. He was tall, handsome and thin. THE NERVE!!! My next Dr. listened to me and now I'm on a med that works just as well without the weight gain. I'm back to 108lbs and I feel good in my skin again!!! Take control over your life.