I agree it is on an individual basis but it can be a life time commitment. There are a lot of variables that come into play.

A lot of information available suggests therapy as well as meds. Depending on cause, depth, duration, reaction to meds, reaction to therapy, etc. no one can really give you a complete answer.

She may or may not have to use meds all the time. Be aware also that dosages and even the drugs themselves my also change.

Her medical team will make the determination. Your wife and possibly you too (if she allows) should be an acctive part of the process.

I wish you both the best.