Ok here's my short story I was on Seroquel for a long time but came off it last March because it caused me to be pre-diabetic and high triglycerides. I instantly went into a mixed episode. We ended up trying Saphris (allergic to it), lithium ( allergic to it), Haldol (loved it, but was only for temporary use and pushed me into a depression), and then latuda (nightmare, it didn't metabolize right). So I had to go back on Seroquel, I'm on 400 mg. I always seem to swing on the high side and I only sleep 2-3 hours without it. I'm also allergic to abilify, Zoloft, and zyprexa. I've been on a few other APs but I can't remember what and why I came off of them. Oh and I'm also on 400 mg of lamictal. My pdoc thinks I'm allergic to an inactive ingredient. Is there any other med (AP or something else) out there that is strong enough for sleep, and then if it wasn't an AP add an AP that I'm not allergic to. I have to be on a mood stabilizer and an AP. I'm sick of this whole weight thing, but I need the sleep and stability. Yeah when I came off the Seroquel last March I dropped 30 lbs instantly and I eat like a rabbit.