I've taken medication since 2004. My problem with them is nausea, as well. I've recently discovered that by drinking a lactose free one shot latte I can take the medication without becoming nauseous. As for the medication's efficacy, well, I've always been poor at taking my prescribed regimen, thus, I'll refrain from claiming that medication doesn't work. I also don't notice when I'm ill and that can be disconcerting, especially, when it should've been obvious to me that what I'm doing doesn't make any sense at all.