I have not taken latuda; however, it works great for my sister. Her only complaint is weight gain; however, she has always battled an eating disorder as well, so this may come into play because she is not overweight.
For me most recently, lamictal worked for a couple of years for bp symptoms, but the mania eventually returned and I couldn't go any higher on the lamictal dosage, so I am now taking lithium. It is working very well. So much so, that I feel subdued. My pdoc says that it is not uncommon to miss the mania at times.
Bluemountains