For me it was finding the right medication.....been on them since the early 80's.....Prozac the first......now switched from wellbutrin to remeron....really helped with sleeping....depression.....been 2 years without a major bout.....(15 MG) taken at night before bed. Only side effect...put on 20 pounds....but hit the gym that much harder ....lost 40......don't give up....I like the fluidity thought ......always changing...I agree your body and brain are different everyday.....ever changing......best of luck