There is straight Seroquel and Seroquel Xr two very different medications as to how people can react to them.

I'm going to go out on a limb and assume your on the XR. Altho that medication gave me the best sleep in my entire insomiac life and slowed my brain down a first in my lifetime also.. As I am anorexic, No way to tolerate the weight gain despite my not eating more and the constant deep down hunger even if your so full of food you couldnt fit in a single tic tac , you will try anyway..

I gained weight ,it had to go. Damn shame Big Pharma churns out medications that not only cause physical problems that weight gain always brings but our self esteem is often already fragile. Altho they have spit out a few that do seem more " weight neutral" than most in the past 10 years.

There are always options to try.. back when I took Ap's and what not I found Invega to be the only one that I had Zero side effects on...

Don't settle, Push to find the very best medications that allows you the best possible bipolar control