Quote:
Originally Posted by alecc
Hello, if ssri/srni and dexedrine don't mix well then this would be a problem cause then what shall I take for depression,gad,ocd? A TCA would mix even less with dexedrine. And a non-serotonergic antidepressant like wellbutrin also wouldnt work. I also tried wellbutrin already and it didnt work. I know buspar but from what I heard it usually sucks and doesnt work at all. I also dont think that buspar is for depression.
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Serotonin syndrome is incredibly rare. Most psychiatrist go their whole career and see maybe one case. It's more a theoretical concern than a real one.
I wouldn't worry about combining an SSRI or an SNRI with Dexedrine or Adderall or whatever. I'm on vyvanse and an SNRI and Brintellix, which is also a serotoninergic agonist/antagonist and previously, I've been on both Dexedrine and Adderall while being on at least one high dose SSRI, I've never had anything close to serotonin syndrome.
Buspar pretty much sucks. If it works, it works great for like 30% of people who try it for anxiety. It does nothing for depression.
A TCA is a serotonin/norepinephrine/dopamine reuptake inhibitor (hence the name). It would interact with Dexedrine just as much. Your risk of serotonin syndrome is just as high with a TCA. That being said, personally, I think TCAs are great for GAD, OCD and depression, all in one med. That might be a good drug for you.