I have had a lot of trouble getting my meds regulated or finding the right “cocktail” as my Dr. Calls it. About six months ago I was put n Seroquel 200mg at night and 50mg during the day. It worked pretty well for a while; then last week he had to change it to 800 mg Seroquel XR because I haven’t been doing well at all. So I am starting a new game. The only thing I don’t like about the Seroquel is the weight gain; I have gained at least 35pds; so I’m looking at possibly joining weight watchers to help with that.