I went through something similar a few years ago. Always worried other people were focusing their negative attention on me. I'd get defensive about anything anyone said, and got so paranoid that I'd stay up all night just to make sure no one broke in while I slept.

Eventually, I just had to let it go. I forced myself to go to sleep at night, and made an effort to stop thinking everyone's out to get me. I'm still working through self-esteem issues a few years later, but at least now I can leave my home without worrying that something bad is going to happen to me. Medication helped me a lot with that particular problem. Just got the noise to settle down in my head enough that I could look at things rationally.