Well, here's an opinion you probably don't see very often...

I've been on Effexor XR for just over 4 years. I've had various doses all the way up to 450mg daily. Currently I have been stable at 150mg for 3 years. I wouldn't think of going a day without it. Unfortunately there has been a day or two here and there where I have misloaded my medication organizer and failed to take the Effexor. Horrible! Just one day without it and I felt horrible. Many of you have commented about the 'numb' feeling you get with the Effexor. I totally appreciate this feeling. Given the choice between how I was before the Effexor and how I am now I don't even have to think twice about not taking the Effexor. I have no desire to discontinue the medication. I'm on other psychiatric meds as well and they all serve their purpose, but I do feel the Effexor in particular has been a lifesaver for me.