Hi there....I have been on Latuda for 1 1/2 yrs. I have pretty bad depression (isn't it always) along with severe panic. My pdoc put me on this when I started obsessive negative thoughts about myself. It took a couple of weeks but it did finally help. The thoughts are not so much as an obsessive thing for me now, although I generally feel pretty crumby about myself anyhow. I will warn you though, definately take this at night because it is very sedating. I have to take it two hours before bedtime in order to be able to get up for work the next day and not feel foggy.
Do give it a go.....Dr's are using this med more and more for a greater spectrum of psych issues. And, of course, everyone responds differently to each med, remember that.
Good luck with it. I hope it brings you some peace. I totally understand you when you talk about all the craziness inside your head!

Oh yeah, I am now on 120mgs of this which is pretty high. I started at 20.