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Hi pande882
The smaller the Ki number, the stronger the interaction between a drug (or anything else) and a protein (eg, alpha-1 adrenergic receptors) is.
So, from your data:
Trazodone has a stronger interaction with α1A than Mirtazapine (Ki values of 153 nM and 500 nM).
Trazodone has a weaker interaction with α2A than Mirtazapine (Ki values of 728 nM and 20 nM).
Trazodone has a weaker interaction with α2C than Mirtazapine (Ki values of 155 nM and 18 nM).
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