Im in the same category as you meaning ive really immersed myself
into all of the published info about POTS. I feel based on the new research, leaked info, and success of midodrine, that POTS is clearly its own sutoimmune disease classified by alpha antagonistic and beta agonistic antibodies. Unfortunately for me I just cant sleep without trazodone or remeron.. Unless i take xanax. I also take melatonin and benadryl nightly. I really need to know the lesser of two evils, traz or rem, when it comes to which is more of an alpha antagonist. I think youre right, its probably traz. I think a lower number means more of an affect. I also think the 'cure' for pots is PEX, IVIG or maybe prednisone combined w exercise.