I was put on Remeron this past winter when my other anti-depressant lost its punch. I'm curious if anyone who has used or is using has had any unpleasant side effects. It has worked very well in keeping my depression in check..although I put 25 pounds of extra weight on in no time at all. My P Doc did warn that I had a 50-50 chance of either gaining or loosing weight...Im trying to weigh the benefits of being healthier mentally...but physically I know its not good for my heart...joints...ect. Just curious if anybody else can elaborate on this medication....Thanks....Artie