I don't think natural remedies only work because of the placebo effect - certainly no more than the drugs created by the drug overlord companies.
I don't care if someone doesn't want to try them, but they are no less real than the plastic stuff put out by the chemists. I have used them to quite good effect - not for depression but for physical things like infection (raw honey) and so forth as well as a specific ptsd situation (sacral cranial energy work). And I swear by acupuncture.