I have chronic fatigue , I have Bipolar I and Fibro. They feed off each other in my case.

You are on a pretty steep dose of Seroquel and then Klonopin and a dash of Effexor to top things off , that's a chemical mixture that kind of all fight against each other, So your medications could be a possible part of the issue . Are you able to get regular exercise? I know who wants to exercise when they are tired right? but it does help.

Side note .. when was the last time you had a full physical exam with blood testing? Thyroid and hormones can easily make you exhausted. Request getting your Vitamin D levels checked also.

How are your sleeping habits? good sleep hygiene? as in go to bed at ____ and get up at _____ every day , even on days off. Some people need 11 hours some people need 5 or 6 a night everyone is different.

Welcome to PC