I started taking Effexor ER just this January and noticed an improvement in the level of my anxiety -- it especially worked with these panic attacks that started up in December. But I still have some anxiety so I'm also on Klonopin 1mg. However, it seems so many of you have had serious issues with Effexor, so now I'm getting worried... especially if I have to come off of it. Fingers crossed that I'll be an exception to the trend...?