Whitecrosses, glad you are facing your challenges head on. Your psychiatrist or therapist are the best source for info. Also your pharmacist should be able to tell you about interactions and side affects.

There are other posts and articles that relate to your questions
Psych Central - Search results for Wellbutrin side affects combining Brintellix

As far as costs go, best to talk directly to your insurance company. If you must private pay mail order like Caremark will often save quite a bit on 90 day supply if you can get prescription from pdoc. Make sure they are working for you before bulk ordering.