Wow. I get exhausted when I take 25 mg. Maybe that's just because I don't take it that often anymore -- maybe 15 days a year. I can't imagine taking 1600 mg plus valium and still being awake. I'd probably sleep for a week. That's some intense mania, and I hope the higher dose of Seroquel kicks in soon. At least your manic urge is to start cleaning things, though.