Social media works relatively well, in my opinion, to help people with busy lifestyles (like me) stay in touch with family and friends. With that said, the most meaningful kind of relationship you can form with a person, in some respects, can only be done through interaction in person. Going on to some points that haven't been discussed in posts above:
Advice for disabled people who have trouble leaving the house: get people to come over and visit!

Have family or people you're living with help out and plan times to get people to come over!
Advice for meeting "smart" people. Well, personally I have an issue with the concept of what it means to be "smart" - does it mean book/school smart, street smart, etc. I think each one of us is smart in some shape or form and we all have things to teach each other and learn from each other. There are many kinds of 'smart' in my opinion. What kind of 'smart' are you thinking about, OP?