I've heard such varying views on this, and would like some more information. (The med we're trying now doesn't seem to be cutting it so far, although that might change -- we can hope.)

My last pdoc took me off Wellbutrin, because of the seizure risk, which he said was dangerously high. My current pdoc says that he's never seen a problem with it, as long as you follow basic precautions in titrating up to a therapeutic dose. The drug info I've seen says that the risk is between one in two hundred and fifty and one in one thousand.

Now, the first doctor discontinued it because my skull was fractured in a car accident when I was a child. The new doctor says that he's prescribing it now for a man who has had five serious concussions over the past decade, with no problems. (He didn't say what dosages were involved nor how long the fellow has been taking it.) I do realize that there's no way to say for sure that it's safe or unsafe, and I realize that the risks increase as the dosage rises above 400 mg per day.

For what it's worth, I also have an eating disorder, but it's limited to restrictive eating -- no purging, no laxatives, etc.

Can anyone offer any other information? Thanks.