I'm sorry you are going through this. I wound up having my Seroquel dose increased to 1500 mg and went back on oral valium which I am taking in 2 doses as I get sleepy. It works some nights and some nights I don't sleep at all. I'm on 1/3rd of my AD and that's been just about too much so that's tricky. I slept last night so tonight may not be good. I'm hoping it is but I don't think I've had 2 good nights together yet. My psychiatrist has been good about staying in touch and I see her in less than 2 weeks so hopefully we'll get things more under control either before then or when I see her. Right now my biggest fear is that I'm going to crash into depression being the predominant mixed symptom and I won't have AD in my blood to help. But I can barely tolerate what I'm on so going up isn't an option. Yesterday I had only 3 hours of sleep but today was better. Hopefully it will be better again tonight although I'm much less exhausted.