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The argument runs that different people react differently. I no longer buy that. Human beings aren't quite that individually differentiated. Everyone who drinks enough ETOH gets drunk. Everyone who smokes enough weed gets stoned. Everyone who takes just about any illicit drug reacts in a predictable way . . . which is why people buy the stuff. But pdocs prescribe all these magic substances that affect different people in vastly different ways. Yeah, because people differ in their degree of credulity - their ability to buy B S.
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I have to disagree with your generalized thoughts here. Not everyone who smokes what you consider to be enough weed gets high....I know a few people from back in the day who didn't get high no matter how much they smoked or how potent the weed was. Not everyone reacts the same way to illicit drugs as there is certainly less control over how they're made not to mention people's metabolism is different, size is different, a dose that could mildly affect a larger person might kill a smaller person.
My daughter and I have been prescribed some of the same meds over the years and neither one of us has the same reaction to those same drugs. Whether they are psych drugs or medical drugs, we both had way different experiences with them. I've seen it happen to many folks I've known over the years....the term "different strokes for different folks" comes to mind here.
We can all have our own opinions about medications and big pharma, but please be careful when generalizing.....no one is exactly the same, there can be lots of folks who have horrible reactions compared to lots of folks who have good experiences with these drugs. Please, let's not insult one another with generalizing.