I am always on huge doses of sedatives. Once I went to my family dr with a sinus infection or something and he was going through my meds, updating doses and things. I said 3200 mg of Depakote and he looked at me oddly. Then he went through my ativan dose and lithium. A minute later he got to 600 mg of Seroquel and he said "I've never seen anyone on that much medication AWAKE before!!". I was just fine....but my body eats sedatives like it is a hobby so it was just funny. I seem to have somehow devoted my life to seeing how much sedation I can tolerate without being drugged. Thus far we know a LOT. (Although a few meds did zombiefy me but they also had bad side effects that required stopping them).