I think the meds affect each person differently. I take Depakote and it makes me forgetful and sort of lazy relative to things like going to the gym. I'm also tired on a regular basis and crap out at 9 on occasion. But I just try to stay mindful and motivated to do things that work for me. IMO, everything is a balance - the meds and the lifestyle. The meds are supposed to help me remain "mellow" or "centered" but right now, I'm listening to "Let There Be Rock" by ACDC.......it isn't exactly a *centering* song! I just go with what I think works in combo.