I have been on Pristiq and it is a very 'activating' anti-depressant. Even though I am on Lithium it made me agitated and a little manic. It did get rid of the depression though so hopefully the Olanzapine and Lithium will put a lid on the mania and allow you to still experience a lifting of the depression. All the best.
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Bipolar 1 with psychotic features
PTSD
"Phew! For a minute there I lost myself."
'Karma Police' by Radiohead
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