i can only tell you what i have heard as i have never had problems with this. my old therapist used to talk about this re: other patients he had that had this problem and said that docs prescribed antidepressants that they took when their periods were coming up to handle the mood swings. they only took them to manage their moods when cycling. i also worked with somebody who got really moody during that time and discovered if they took pamprin, the mood swings abated.