I am definitely frustrated with myself. I have been in a downward spiral for several years, medications work for a short while and, then, it's back to the same old. I have no motivation to even remove my butt from the couch... all day, every day... I even sleep on the couch. My mind is filled with things I want to do, things I should do as a wife and homeowner, but when it comes to execution - Nothing! I have been reading on this site about the benefits of adding certain medications to antidepressants I'm already taking, which is 300mg of Effexor XR - I'm going to inquire about the success of adding Remeron or Abilify - maybe if I can get my mindset healthier, the motivation will follow. Good luck to everyone. If you have tried anything that you found worked, please let me know. Thanks to all!