Pmdd was a massive issue for me as a teen. I was on yaz BC for 8 years and it helped but I was kind of forgetful at taking pills.

I know mirena can be an issue for people who are meds sensitive and bipolar, but it helped me. I am one of the 10% that rarely has a period and because of that my PMS/pmdd is basically non existent. I've had both highs and lows while on this med so I'm pretty sure it's not contributing to my issues other than positively.

As a teen, 90% of the times I SIed were in the 2 week period of my PMS. I definitely think PMS/pmdd can coexist with a wide variety of illnesses.