seems like i'm getting a build-up of side effects from 60 mg. cymbalta i've been on since april. caused a serious mental fog and confusion as well as sleepiness. now, i have additional issues that are off and on. nausea, diarrhea, and strange sensations in my head. i've seen my pdoc 2 days ago and decided to lower the dosage to 40 mg. i'm starting on that 40 mg. dosing tomorrow. i know it takes awhile for the side effects to subside. but, it freaks me out because the symptoms can be all kinds of other things, including depression. i know i just need to hang in there for at least a week on this dose. i'm not thinking straight. couldn't do anything today because i end up going in circles in my living room and making myself sick. i know this doesn't make sense - it doesn't to me. it's like i'm trapped. i'm like a scientist, and i can't even manage researching because it causes me further confusion. i'm treatment-resistant, so it's really tricky in finding the right treatment for my mdd. i hope this doesn't sound like i'm reaching out for straws, but i feel that way. i've had mdd since i was 20 and that's been 15 years now. it's a real nightmare. i just don't want to lose hope in finding the right treatment. no, i can't do ect treatments because i can't see how it can be safe for me with my stroke-related brain damage and the depression-related memory deficits. also, put this on top of this mental fog i'm in, there's no way i will do ect.