I just want to address a couple of things you mentioned. The first one is lack of adequate protein. I run into that problem because of lack of money and sometimes because of lack of energy or motivation. I typically get anxious and more depressed and my energy level drops and I have muscle weakness when I'm not getting enough protein. It really is important, even if it's Boost or Ensure.

The other thing is your sleep disturbance. Even if you are discouraged about treating your depression with meds, trying to get your sleep straightened out will make you feel better physically and mood-wise. I feel like I've taken all the meds, too, but one that I hadn't tried was low-dose mirtazipine/Remeron for sleep. I started taking it in March and it has changed my sleep pattern from 2 years of being awake until 3-4 am then sleeping until 11-12 but still feeling exhausted to waking up at 7-8 am. It's such a relief not to be exhausted at night for 3-4 hours, too tired to do anything, but unable to sleep.

I found the treatment resistant thread when I first joined Psych Central and could really identify with the stories there. A lot of long-suffering, tired people have posted their stories there.

Oh - I get where you're coming from regarding no money for eating out or social things like that. I still haven't solved that problem. I used to have a "meet for coffee/tea" friend, but she moved.