Well, I'm of pretty high intelligence and haven't had those problems. It is not unusual for someone in the middle of treatments to be disoriented and have memory issues, but most often, those problems diminish after treatments are over, so judging a person's long-term outcome while they are in the midst of treatment isn't really doable. During my husband's treatments, he was very disoriented, but within a few weeks of the end of this treatments he was completely fine.