Thanks for those links. I've had several wake up calls, and a big one just yesterday (lost another friend because of my depression), but it's like no matter how hard I try, the sadness and anxiety just don't go away. I really am starting to think it's because my thyroid isn't working right. Kind of like how someone with a true chemical imbalance can't help how they feel, I really think my thyroid not working is causing my brain to not let me be happy. I've been to so many doctors though and no one knows why the meds aren't working.