Took Wellbutrin over 10 years, holdover from when I was diagnosed only with depression. Stopped it about two months ago because while I long knew It wasn't treating my depression , in recent months anxiety is more prominent and Wellbutrin may have been doing more harm than anything. I thought i might notice some difference after d/c since I took it so long but nothing, not any more sleepy or depressed than usual. I was thankful to trim down my med list by one.

I still take Rememon for an AD, I don't think it's effective for my depression but taken it almost 10 years now and It may be helpful in other ways, maybe anxiety. Mostly I just stay on it because it's cheap doesn't cause noticeable side effects, and doesn't seem to cause
harm. If someone with BD is looking for an AD Remeron is unique and probably had less risk for mania. For major depression its probably more effective than an SSRI/NRI but can cause drowsiness when started so not that popular. For bipolar depression I haven't seen evidence that it works but being least likely to cause harm is a plus if you must add an AD.

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