Woah.......um, how many APs have you been on? Because Clozaril is supposed to be the last resort drug when all the others have failed. I don't know if it still does but even its' website used to say that. My pdoc and I have discussed it several times but have always agreed to try something else first (hence the loxapine, as rarely used as that is). I would be very, very wary of going on Clozaril unless there were no other options because of this.

I looked, it still says that it is for people who have failed standard antipsychotic treatment. And to me that means failing everything, and failing meaning "cannot take this med because my body cannot handle it, I am tolerating every side effect I possibly can" because this stuff is potentially really hard on your body, and it also would mean trying some older meds as routine meds (I am pretty certain that if I fail loxapine Clozaril will be start to become a much more likely med because I have failed many meds and some of the remaining ones are not especially safe for me because of some serious past reactions. I have been on: Abilify, Geodon, Risperdal, Seroquel, Seroquel XR, Latuda and loxapine. I am allergic to Invega so that's out and Saphris can't be tried with Seroquel. And I still haven't reached the point where Clozaril has been more than a discussion. I know my pdoc was glad it was on my insurance, although I'm sure I can't afford it.

The FDA didn't even approve it for many years because of the side effects with white blood cells and it is approved as a last resort med only. I think it is required to say "last resort" or something of the sort.

The loxapine I am taking now is actually a cousin to clozaril but I haven't been able to figure out how closely related they are. Loxapine is definitely safer by far. They are the only 2 meds in their class if I remember this correctly.

I would be very, very wary of a dr who already tends to dose really high and with polypharmacy (and I'm on a lot of meds saying that but mine has logic for each choice that I'm aware of and I know why I'm on each and why I'm on each dose (and they were my choices)--and hopefully I'll come off my mood stabilizers soon as I'm on more AP) going anywhere near Clozaril.

I am sorry if this is overly blunt but I would run really far away from your particular dr and a prescription for Clozaril.

I am glad that you got things for now, but I wouldn't let him give me Clozaril for anything. I wouldn't take Clozaril from anyone but a top dr with a lot of expertise and I'd want to know why I hadn't been on any number of other drugs before that came up.