Have you ever been on antidepressants or mood stabilizers? I'm bipolar and spend a lot of time in depression. There are no environmental changes or activities that I can find that will pull me out of it. Meds can sometimes make a real difference if you can find the right one(s) for you. I've been off and on with them for several years. But since I've been off, I've noticed mine getting increasingly worse too. I hope you will take care of yourself and find whatever help you need to feel better!