I don't have direct experience, but my daughter does. She's only been with 3 guys her whole life, but she caught herpes from #2. She's now happily married. The key was her being up front and her and her husband understanding the disease and how to deal with it. Proper precautions, watching for outbreaks and using protection have made their life just fine and if you asked them, they probably would even have to think about it since it's such a non-issue for them.

So I think the key is being up front and honest and working together to make things work out.