I was simply going off the OP's original statement that the toddler "refuses" to open his eyes, and also the fact that their pediatrician doesn't see this to be a medical issue. And I doubt it is a mental issue either. Perhaps they need to just let him sleep if he is sleeping rather than waking him up before he is ready to wake up. Otherwise he is behaving normally, doesn't seem to be bothered by his eyes being closed, pediatrician doesn't sound particularly worried about it . . . Toddlers can be mysteries sometimes, but we can often jump to thinking it is something seriously pathological when it could be as simple as a toddler who would have rather slept longer, who perhaps is being asked a lot to open his eyes by parents who are anxious about him doing something differently and sees it as a bit of a game . . . who knows? Give it some time. Sit back and just observe for a bit since there doesn't seem to be anything medically going on. If it's still going on and particularly if there seems to be anything else going on with it, then of course, get it checked out, but people saying go to the ER right now over this is just a bit much since there is nothing apparently medically going on according to their own pediatrician who they've already consulted about this. All the ER would do is say go see your pediatrician and let him refer you somewhere if there seems to be a serious problem. Unless there is evident pain, dizziness, vomiting, other indications of something more going on that closed eyelids, the course of action generally is to just wait and see if this persists and report back with progress or lack thereof.