Me. Don't know. When I was a toddler I got really abused, hence my other issues and the triggering of bipolar disorder. It has maintained its level of effectiveness through the years. I'm now 47, and through present meds, it's so like nonexistent. I really don't feel like it got worse for me, until I got medicated and then tried to quit meds. I feel that I screwed myself by getting junked out on meds...but at least I'm stabile. Yaaaay.

But according to research and studies, the mania aspect wanes and it just turns into depression. I just don't see it.