You need an open conversation while he's baseline. Where expectations get set, so that both of your needs can be met.

It is indeed possible to have a healthy relationship with someone who has bipolar, or any other mental health issue. It will sometimes require more work than other relationships might require.... but it's most certainly possible.

It sounds like you have opposite needs. Have the two of you ever talked about having a family? Because that would be a big thing for him - he cannot handle his depressions by ignoring the world if he has children in his life. Ignoring the world completely is not a healthy coping skill, and yes, that should probably be worked on by him!

That said... you can't make him change, and if he can't or isn't willing to make any changes right now then it's your call whether or not to stay and put up with it, or cut your losses and move on.