I'm on lexapro (antidepressant) Largactil and Abilify (antipsychotics) and benztropine/cogentin (anticholinergic). But I don't have bipolar (I have c-ptsd, anxiety and depression), so I can't say how benztropine would work for you. It is said to have a sedating effect, so too does seroquel. I'm not sure about latuda. It's best just to notice the changes that take place and keep your doc informed. Don't be afraid to speak up if it's not going well.