Is he also seeing a psychoanalyst? Meds are only part of recovery. Whatever was going on inside him before, turmoil, isn't going to disappear with meds. I use the word turmoil because he left you twice and he's becoming worse, as you say. Yes, sleep can exacerbate illnesses, yet, if he's unable to get along with you, behavior, which i presume since you're posting here, then there's something going on inside of him.
Sorry you're both struggling.