To the point: does music ever depress the hell out of you?

I'm a music lover. I'm a musician. Music is infinitely more than a pastime or amusement for me; much more than background noise.

So, am I the only one that is so moved by music that it hurts to listen to at times? The only one that tangibly feels terrible - even from favorite upbeat, or beautiful music?

I know that I am not, so please share what is is like for you. What does it feel like when music make you feel bad? Do you feel betrayed? Do you feel abandoned?