I have been wondering about that myself although in a slightly different way. I was in a pretty bad mixed episode and Latuda snapped me out it. I stayed on it for nine months till I could not take the side effects anymore. In the beginning it was a god sent, but as I improved I was more critical of the side effects and how they were affecting my day to day life. So I went off it. But I do have that feeling in the back of my head "what if I need it again. Will it lose it efficacy if I use it on an as needed basis? Or can I keep it in the arsenal in times of need." It scares me quite a bit sometimes like I am over vigilant about every little thing