It sounds like you have a decision to make. Do you want to loose weight, but take the risk of making a pre existing condition worse. Do you want to bear the burnden of having to deal with the possibility of having complications related to your weight (diabetes, high blood pressure, high cholesterol etc.)? Do you have self esteem issues? Would this in long term help you get off of/on a lower dose of the anti depressants? Your doctor perscribed it because 1 of 2 things, either he thought the risk was worth it, or it's something new and he dosent know the risks.